Methotrexate: should it still be considered for chronic calcium pyrophosphate crystal disease?
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چکیده
منابع مشابه
Methotrexate: should it still be considered for chronic calcium pyrophosphate crystal disease?
Chronic calcium pyrophosphate crystal arthritis is a clinical consequence of the formation and deposition of these crystals in joints and can result in persistent arthritis. Curative treatment would require the removal of crystals from joints and tissues, but to date all agents tested have proven ineffective. Management of the inflammatory manifestations of chronic calcium pyrophosphate disease...
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متن کاملMethotrexate in chronic-recurrent calcium pyrophosphate deposition disease: no significant effect in a randomized crossover trial
INTRODUCTION Calcium pyrophosphate deposition (CPPD) may cause severe arthropathy, major joint destruction and treatment options are limited. The aim of this study was to test the therapeutic efficacy of methotrexate (MTX) in chronic or recurrent CPPD arthropathy. METHODS Patients with CPPD arthropathy were randomized to receive either weekly subcutaneous injections of 15 mg/week of MTX or pl...
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ژورنال
عنوان ژورنال: Arthritis Research & Therapy
سال: 2015
ISSN: 1478-6354
DOI: 10.1186/s13075-015-0598-1